Two people have been flown to hospital following a serious six-vehicle road traffic collision on the A66 near Powter Howe.
Emergency services including two air ambulances were called to the scene at approx 12:55pm.
Two BEEP Fund Doctors were called to the incident.
A BEEP Fund spokesman said: “Advanced interventions were performed by one of the BEEP Doctors as well as the Doctor and paramedic crews from the two Great North Air Ambulance helicopters that were also mobilised to the scene in order to assist the most seriously injured, who were then flown to Preston and Newcastle.”
A Cumbria Fire and Rescue Service spokesman said: “Two fire engines from Cockermouth and Keswick attended a road traffic collision with persons trapped on B5291 Bassenthwaite lake, Cockermouth.
“Fire fighters released one casualty from a vehicle.
“Two casualties were taken by air ambulance to hospital and one casualty was taken by road ambulance.
“Crews were in attendance for one hour and forty minutes.”
The A66 was closed in both directions between A591 (Keswick) and A595 (Cockermouth).
The road reopened at approx 5:40pm.